Improved Diagnosis of Orthopedic Implant-Associated Infections by Inoculation of Sonication

نویسندگان

  • María Eugenia Portillo
  • Margarita Salvadó
  • Andrej Trampuz
  • Ana Siverio
  • Albert Alier
  • Santos Martínez
  • Daniel Pérez
  • Juan P. Horcajada
  • Lluis Puig
چکیده

Fluid into Blood Culture Bottles 2 María Eugenia Portillo*, Margarita Salvadó, Andrej Trampuz, Ana Siverio, Albert Alier, Lluisa 3 Sorli, Santos Martínez, Daniel Pérez, Juan P. Horcajada, Lluis Puig 4 5 Microbiology Laboratory, Reference Laboratory of Catalunya, Barcelona, Spain 6 Center for Septic Surgery, Charité University Medicine Berlin, Berlin, Germany 7 Department of Orthopedic Surgery, Hospital del Mar, Barcelona, Spain 8 Infectious Diseases, Hospital del Mar, Hospital del Mar, Research Institute (IMIM), Barcelona, Spain 9 10

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Improved diagnosis of infection associated with osteosynthesis by use of sonication of fracture fixation implants.

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TITLE: Improved Diagnosis of Infection Associated to Osteosynthesis by Use of Sonication

20 Previous studies have shown that sonication-fluid cultures from removed devices improved the 21 microbiological diagnosis of orthopedic implant-associated infections; however, few of these 22 investigations have applied sonication to the removed fracture-fixation devices to evaluate its 23 utility as an adjunctive diagnostic tool for osteosynthesis-associated infection (OAI). We 24 compared ...

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Concentration of Sonication Fluid through Centrifugation Is Superior to Membrane Filtration for Microbial Diagnosis of Orthopedic Implant-Associated Infection.

Microbial identification of orthopedic implant-associated infections using sonication fluid (SF) submitted to a concentration step by membrane filtration (SMF) was compared with the standard centrifugation (SC) method. Among 33 retrieved infected implants, sonication identified microorganisms in 26 (78.8%). The sensitivity of SC was higher than that of SMF (78.8% versus 30.3%; P < 0.001).

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تاریخ انتشار 2015